Preheat your oven to 375°F (190°C) and grease your aluminum pans.
Cook the rotini pasta according to package instructions until al dente. Drain and set aside.
In a large skillet, brown the ground beef over medium heat. Add diced onions and bell peppers, cooking until softened.
Stir in minced garlic and Italian seasoning, cooking for an additional minute until fragrant.
Add marinara sauce to the skillet, stirring until well combined. Simmer for 5-7 minutes.
Combine cooked pasta with the meat sauce mixture. Mix in half of the mozzarella and parmesan cheese.
Transfer the mixture evenly into prepared aluminum pans. Top with remaining mozzarella cheese, parmesan cheese, and pepperoni slices.
Cover pans tightly with aluminum foil and label with baking instructions if freezing.
Bake covered for 25-30 minutes. Remove foil and bake for an additional 10 minutes until cheese is bubbly and golden.
Let cool slightly before serving. Enjoy your delicious Pizza Pasta Bake!